SCHEMBL10583136

SCHEMBL10583136

CC1CC2C[CH]C1C2(C)C

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5935626 0.67 TSHR (0.34) TSHRMAPK1
SCHEMBL847951 0.67 TSHR (0.34) TSHRMAPK1
SCHEMBL847288 0.67 TSHR (0.34) TSHRMAPK1
SCHEMBL1588075 0.67 TSHR (0.34) TSHRMAPK1
SCHEMBL9817562 0.67 TSHR (0.34) TSHRMAPK1
SCHEMBL12479098 0.60
SCHEMBL5896876 0.57
SCHEMBL6939096 0.55 TDP1 (0.38)
SCHEMBL1870221 0.55
SCHEMBL13127148 0.55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4822635-A Sweetening with L-aminodicarboxylic acid esters GENERAL FOODS CORPORATION (US) 1989-04-18 US disclosed
US-4788073-A Sweetening with L-aminodicarboxylic acid alkenes GENERAL FOODS CORPORATION (US) 1988-11-29 US disclosed
US-4788332-A ARTIFICAL SWEETENER GENERAL FOODS CORPORATION (US) 1988-11-29 US disclosed
US-4781927-A Sweetening with l-aminodicarboxylic acid esters GENERAL FOODS CORPORATION (US) 1988-11-01 US disclosed
US-4766246-A L-aminodicarboxylic acid esters GENERAL FOODS CORPORATION (US) 1988-08-23 US disclosed
US-4760175-A L-aminodicarboxylic acid alkenes GENERAL FOODS CORPORATION (US) 1988-07-26 US disclosed
US-4698231-A Sweetening with L-aminodicarboxylic acid amides GENERAL FOOD CORPORATION (US) 1987-10-06 US disclosed
US-4678675-A Sweetening with L-aminodicarboxylic acid alkenes GENERAL FOODS CORPORATION (US) 1987-07-07 US disclosed
US-4678674-A Sweetening with L-aminodicarboxylic acid amides GENERAL FOODS CORPORATION (US) 1987-07-07 US disclosed
US-4654219-A ARTIFICIAL SWEETENERS GENERAL FOODS CORPORATION (US) 1987-03-31 US disclosed
US-4622232-A L-aminodicarboxylic acid alkanes GENERAL FOODS CORPORATION (US) 1986-11-11 US disclosed
US-4622417-A DIETETICS GENERAL FOODS CORPORATION (US) 1986-11-11 US disclosed
EP-0199258-A2 L-Aminodicarboxylic acid amides and an edible composition containing same GENERAL FOODS CORPORATION (US) 1986-10-29 EP disclosed
EP-0199257-A2 L-Aminodicarboxylic acid esters and an edible composition containing same as sweeteners GENERAL FOODS CORPORATION (US) 1986-10-29 EP disclosed
US-4619834-A Sweetening with L-aminodicarboxylic acid aminoalkenoic acid ester amides GENERAL FOODS CORPORATION (US) 1986-10-28 US disclosed
US-4619782-A L-aminodicarboxylic acid gem-diamines GENERAL FOODS CORPORATION (US) 1986-10-28 US disclosed
US-4603012-A L-aminodicarboxylic acid alkanes GENERAL FOODS CORPORATION (US) 1986-07-29 US disclosed
EP-0186173-A2 L-Aminodicarboxylic-(0-cycloalkyl)-L-aminocarboxylate alkyl esters, an edible composition containing same as sweeteners and a method for sweetening an edible composition GENERAL FOODS CORPORATION (US) 1986-07-02 EP disclosed
US-4572799-A L-Aminodicarboxylic acid amides GENERAL FOODS CORPORATION (US) 1986-02-25 US disclosed
US-4571308-A L-Aminodicarboxylic acid aminoalkenoic acid ester amides GENERAL FOODS CORPORATION (US) 1986-02-18 US disclosed