Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.59 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10586496 | 1.00 | PTGS1 (0.63) | PTGS1MAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL10552664 | 0.89 | MAPT (0.75) | PTGS1MAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL10552674 | 0.89 | MAPT (0.75) | PTGS1MAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL11874716 | 0.88 | PTGS1 (0.70) | PTGS1MAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL11874725 | 0.88 | PTGS1 (0.70) | PTGS1MAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL10529194 | 0.87 | MAPT (0.75) | PTGS1MAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL10529189 | 0.87 | MAPT (0.75) | PTGS1MAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL11231884 | 0.86 | PTGS1 (0.83) | PTGS1MAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL11231880 | 0.86 | PTGS1 (0.83) | PTGS1MAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL11583209 | 0.86 | PTGS1 (0.83) | PTGS1MAPTHSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321364-A2 | Orally administrable cephalosporin derivatives, and the production and uses thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1989-06-21 | — | — | EP | disclosed |