⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2163135 | 0.86 | ATM (0.34) | — | |
| SCHEMBL10735259 | 0.81 | PSEN1 (0.35) | — | |
| SCHEMBL10894999 | 0.76 | — | — | |
| SCHEMBL10586526 | 0.75 | — | — | |
| SCHEMBL6424617 | 0.72 | — | — | |
| SCHEMBL10588377 | 0.69 | — | — | |
| SCHEMBL3686492 | 0.65 | SLC1A2 (0.35) | — | |
| SCHEMBL10732855 | 0.62 | — | — | |
| SCHEMBL10731634 | 0.62 | MAPT (0.33) | — | |
| SCHEMBL9659633 | 0.61 | GRM2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739017-A | INDUCING THE GRAFT POLYMERIZATION OF A VINYL POLYMER SUBSTRATE AND ETHENICALLY UNSATURATED COMPOUND FORMED BY THERMAL DECOMPOSITION OF AN ADDUCT | THE DOW CHEMICAL COMPANY (US) | 1988-04-19 | — | — | US | claimed |
| EP-0327745-A1 | Diels alder assisted polymer grafting process | THE DOW CHEMICAL COMPANY (US) | 1989-08-16 | — | — | EP | disclosed |
| US-4739017-A | INDUCING THE GRAFT POLYMERIZATION OF A VINYL POLYMER SUBSTRATE AND ETHENICALLY UNSATURATED COMPOUND FORMED BY THERMAL DECOMPOSITION OF AN ADDUCT | THE DOW CHEMICAL COMPANY (US) | 1988-04-19 | — | — | US | disclosed |