Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10586024 | 0.96 | KDM4E (0.39) | KDM4EMAPTALDH1A1RXFP1L3MBTL1 | |
| SCHEMBL10586818 | 0.90 | KDM4E (0.37) | KDM4EMAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL421735 | 0.89 | KDM4E (0.40) | KDM4EMAPTALDH1A1L3MBTL1FAAH | |
| SCHEMBL3875987 | 0.88 | KDM4E (0.44) | KDM4EMAPTALDH1A1L3MBTL1FAAH | |
| SCHEMBL10585560 | 0.81 | KDM4E (0.32) | KDM4E | |
| SCHEMBL10587223 | 0.81 | KDM4E (0.32) | KDM4E | |
| SCHEMBL10586933 | 0.81 | KDM4E (0.32) | KDM4ETHRB | |
| SCHEMBL10584526 | 0.80 | KDM4E (0.32) | KDM4ETHRB | |
| SCHEMBL10586059 | 0.80 | KDM4E (0.32) | KDM4ETHRB | |
| SCHEMBL10584621 | 0.78 | KDM4E (0.33) | KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302401-A1 | Pyridone dyes, process for their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1989-02-08 | — | — | EP | disclosed |