Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | USP5 | P45974 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 10/20 | 0.41 |
| ▸ | CLK1 | P49759 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2038541 | 0.84 | MEN1 (0.48) | MEN1HPGDKMT2AHSD17B10ATM | |
| SCHEMBL2039637 | 0.84 | MEN1 (0.48) | MEN1HPGDKMT2AHSD17B10ATM | |
| SCHEMBL2246082 | 0.81 | TSHR (0.40) | MEN1HPGDKMT2AHSD17B10TSHR | |
| SCHEMBL29508396 | 0.79 | USP5 (0.43) | MEN1HPGDKMT2AHSD17B10TSHR | |
| SCHEMBL28800378 | 0.79 | USP5 (0.43) | MEN1HPGDKMT2AHSD17B10TSHR | |
| SCHEMBL28800377 | 0.79 | USP5 (0.43) | MEN1HPGDKMT2AHSD17B10TSHR | |
| SCHEMBL9219187 | 0.79 | USP5 (0.67) | MEN1HPGDKMT2AHSD17B10TSHR | |
| SCHEMBL9379418 | 0.78 | USP5 (0.45) | MEN1HPGDKMT2AHSD17B10TSHR | |
| SCHEMBL10588967 | 0.78 | USP5 (0.42) | MEN1HPGDKMT2AHSD17B10TSHR | |
| SCHEMBL22749324 | 0.77 | USP5 (0.44) | MEN1HPGDKMT2AHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310950-A1 | Quinoline intermediates for the synthesis of 1H-imidazo[4,5-c]quinolines and 1H-imidazo[4,5-c]quinolin-4-amimes | RIKER LABORATORIES, INC. (US) | 1989-04-12 | — | — | EP | disclosed |