Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.65 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14491041 | 1.00 | CSNK1E (0.65) | CSNK1ETRPA1EPHX1SLC6A2TAAR1 | |
| SCHEMBL13964094 | 1.00 | CSNK1E (0.65) | CSNK1ETRPA1EPHX1SLC6A2TAAR1 | |
| SCHEMBL14491032 | 1.00 | CSNK1E (0.65) | CSNK1ETRPA1EPHX1SLC6A2TAAR1 | |
| SCHEMBL6425554 | 0.85 | EPHX1 (0.62) | CSNK1ETRPA1EPHX1SLC6A2TAAR1 | |
| SCHEMBL11590730 | 0.85 | CSNK1E (0.76) | CSNK1ETRPA1EPHX1SLC6A2TAAR1 | |
| Hydrochloric Acid SCHEMBL9388352 | 0.83 | EPHX1 (0.60) | CSNK1ETRPA1EPHX1SLC6A2TAAR1 | |
| SCHEMBL4508560 | 0.82 | CSNK1E (0.88) | CSNK1ETRPA1EPHX1SLC6A2TAAR1 | |
| SCHEMBL27648870 | 0.82 | CSNK1E (0.88) | CSNK1ETRPA1EPHX1SLC6A2TAAR1 | |
| SCHEMBL7758242 | 0.82 | EPHX1 (0.58) | CSNK1ETRPA1EPHX1SLC6A2TAAR1 | |
| SCHEMBL8761734 | 0.82 | EPHX1 (0.58) | CSNK1ETRPA1EPHX1SLC6A2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0327877-A2 | Peptide-renininhibitors | MERCK PATENT GmbH (DE) | 1989-08-16 | — | — | EP | disclosed |