SCHEMBL1059082

SCHEMBL1059082

COC/C=C/COC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1059084 1.00
SCHEMBL7814020 1.00
SCHEMBL10024576 0.86
SCHEMBL6044888 0.86
SCHEMBL6044884 0.86
SCHEMBL907325 0.86
SCHEMBL2770216 0.86
SCHEMBL907326 0.86
SCHEMBL2770219 0.86
SCHEMBL19418916 0.84 AKT1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5312969-A Linear dicarbonylation of difunctionalized butenes RHONE-POULENC CHIMIE (FR) 1994-05-17 US claimed
US-4633015-A CATALYTIC CARBONYLATION IN APROTIC SOLVENT, HYDROGENATION AND HYDROLYSIS MONSANTO COMPANY (US) 1986-12-30 US claimed
US-4611082-A Production of hex-3-enedioate esters from 1,4 dialkoxy butenes MONSANTO COMPANY (US) 1986-09-09 US claimed
US-11339188-B2 Compounds for the treatment of cancer EISAI R&D MANAGEMENT CO., LTD. (JP) 2022-05-24 US disclosed
CN-114230523-A Benzimidazole derivatives as modulators of ROR-gamma 生命医药有限责任公司 2022-03-25 CN disclosed
EP-3939974-A1 MODULATORS OF ROR-GAMMA Vitae Pharmaceuticals, LLC (US) 2022-01-19 EP disclosed
CN-109071509-B Benzimidazole derivatives as modulators of ROR-gamma 生命医药有限责任公司 2021-11-30 CN disclosed
EP-3582853-B1 CYCLIC DI-NUCLEOTIDES COMPOUNDS FOR THE TREATMENT OF CANCER EISAI R&D MAN CO LTD (JP) 2021-11-17 EP disclosed
EP-2527420-B1 LUBRICATING OIL COMPOSITION JX NIPPON OIL & ENERGY CORP (JP) 2021-09-29 EP disclosed
EP-3408268-B1 BENZIMIDAZOLE DERIVATIVES AS MODULATORS OF ROR-GAMMA VITAE PHARMACEUTICALS LLC (US) 2021-08-04 EP disclosed
US-20210094940-A1 MODULATORS OF ROR-GAMMA VITAE PHARMACEUTICALS, LLC 2021-04-01 US disclosed
US-4633015-A CATALYTIC CARBONYLATION IN APROTIC SOLVENT, HYDROGENATION AND HYDROLYSIS MONSANTO COMPANY (US) 1986-12-30 US disclosed
US-4611082-A Production of hex-3-enedioate esters from 1,4 dialkoxy butenes MONSANTO COMPANY (US) 1986-09-09 US disclosed
US-4533761-A REACTING BUTADIENE AND AN ALKANOL USING A COPPER REDOX CATALYST AND ALKALI METAL HALIDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-08-06 US disclosed
EP-0039486-B1 PREPARATION OF FURAN COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-08-17 EP disclosed
EP-0039486-A1 Preparation of furan compounds E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-11-11 EP disclosed
US-4257960-A FROM UNSATURATED DIOLS, ETHERS, OR ESTERS USING A COPPER REDOX SYSTEM E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-03-24 US disclosed
US-4168379-A Pyridin-3-ols BASF AKTIENGESELLSCHAFT (DE) 1979-09-18 US disclosed
US-4022804-A ADDITION REACTION; SULFONIC ACID BROMIDES, UNSATURATED COMPOUNDS BASF AKTIENGESELLSCHAFT (DT) 1977-05-10 US disclosed
US-3974092-A COMPOUND, 6B, ORGANOALUMINUM COMPOUND, ETHER OF OLEFIN ALCOHOL CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DT) 1976-08-10 US disclosed