Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CD44 | P16070 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155714 | 0.94 | TSHR (0.59) | PDE10ATSHRCASP1TRPA1ATM | |
| SCHEMBL7111743 | 0.86 | TSHR (0.68) | PDE10ATSHRCASP1TRPA1ATM | |
| SCHEMBL71383 | 0.82 | — | — | |
| SCHEMBL33808 | 0.82 | — | — | |
| SCHEMBL29975466 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL27589678 | 0.80 | PDE10A (0.95) | PDE10ATSHRCASP1CYP3A4ALDH1A1 | |
| Water SCHEMBL28781371 | 0.80 | CYP3A4 (0.62) | TSHRCASP1TRPA1ATMCYP3A4 | |
| Hydrochloric Acid SCHEMBL6518172 | 0.80 | PDE10A (0.95) | PDE10ATSHRCASP1CYP3A4ALDH1A1 | |
| Bromide SCHEMBL4051270 | 0.80 | PDE10A (0.95) | PDE10ATSHRCASP1CYP3A4ALDH1A1 | |
| 4-Aminophenol SCHEMBL2684816 | 0.79 | CYP3A4 (0.52) | PDE10ATSHRCASP1TRPA1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4862575-A | Method and apparatus for finishing grooved articles | NIPPON DENSO CO., LTD. (JP) | 1989-09-05 | — | — | US | claimed |