Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MGAM | O43451 | 1/20 | 0.56 |
| ▸ | SI | P14410 | 1/20 | 0.56 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9461850 | 0.86 | GAA (0.54) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL28009465 | 0.83 | GAA (0.61) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL29411100 | 0.82 | GAA (0.41) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL6180806 | 0.81 | GAA (0.58) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL27842787 | 0.79 | GAA (0.56) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL2576619 | 0.79 | GAA (0.56) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL17134667 | 0.79 | GAA (0.56) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL4418314 | 0.78 | GAA (0.61) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL11372768 | 0.78 | GAA (0.45) | GAAMGAMSIMGAM2LMNA | |
| Malonic Acid Diethyl Ester SCHEMBL7792998 | 0.78 | GAA (0.60) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110938620-B | Magnetic immobilized yeast cell and application thereof in synthesis of (R) -4-chloro-3-hydroxybutanoate ethyl ester | 浙江工业大学 | 2021-06-08 | — | — | CN | claimed |
| CN-110938620-A | Magnetic immobilized yeast cell and application thereof in synthesis of (R) -4-chloro-3-hydroxybutanoate ethyl ester | 浙江工业大学 | 2020-03-31 | — | — | CN | claimed |
| CN-101896492-A | Tetriacyclodipyranyl coumarins and the anti-HIV and anti-tuberculosis uses thereof | INST OF MATARIA MEDICA CHINESE | 2010-11-24 | — | — | CN | disclosed |
| EP-0168950-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BECKMAN CORPORATION (US) | 1989-01-11 | — | — | EP | disclosed |
| US-4769386-A | Imidazolylthioalkenoic acids and -alkenols and leukotriene antagonistic composition containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1988-09-06 | — | — | US | disclosed |
| EP-0168950-A1 | Leukotriene antagonists | SMITHKLINE BECKMAN CORPORATION (US) | 1986-01-22 | — | — | EP | disclosed |