Ethylene Glycol

Ethylene Glycol

SCHEMBL10596123

O=C1CCCCC(=O)OCCOCCO1.OCCO

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.56
CA9 Q16790 1/20 0.56
ALDH1A1 P00352 2/20 0.42
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42
TSHR P16473 1/20 0.42
CYP2D6 P10635 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL1242255 0.93 CA1 (0.64) CA1CA9ALDH1A1LMNATP53
Ethylene Glycol SCHEMBL8470596 0.91 CA1 (0.61) CA1CA9ALDH1A1LMNATP53
Ethylene Glycol SCHEMBL5702872 0.91 CA1 (0.61) CA1CA9ALDH1A1LMNATP53
Ethylene Glycol SCHEMBL10770671 0.91 CA1 (0.61) CA1CA9ALDH1A1LMNATP53
SCHEMBL1495330 0.89 CA1 (0.70) CA1CA9ALDH1A1LMNATP53
Ethylene Glycol SCHEMBL173829 0.86 CA1 (0.76) CA1CA9ALDH1A1LMNATP53
Ethylene Glycol SCHEMBL384287 0.86 CA1 (0.68) CA1CA9ALDH1A1LMNATP53
SCHEMBL7105666 0.86 CA1 (0.67) CA1CA9ALDH1A1LMNATP53
SCHEMBL7602098 0.86 CA1 (0.67) CA1CA9ALDH1A1LMNATP53
SCHEMBL7106267 0.86 CA1 (0.67) CA1CA9ALDH1A1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0133779-B1 IMPROVED CONTROL OF TRANSFORMATIONS WITHIN POLYMERS AND PRODUCTS THEREOF RAPRA TECHNOLOGY LIMITED (GB) 1989-12-27 EP disclosed
US-4767804-A REACTING LOW MOLECULAR WEIGHT THIOL- OR CARBOXYL-TERMINATED POLYMER WITH METAL COMPOUND RUBBER BANDS AND PLASTIC RESEARCH ASSOCIATION OF GREAT BRITAIN (GB) 1988-08-30 US disclosed
EP-0133779-A2 Improved control of transformations within polymers and products thereof RAPRA TECHNOLOGY LIMITED (GB) 1985-03-06 EP disclosed