Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.62 |
| ▸ | LTB4R | Q15722 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10795878 | 1.00 | RXFP1 (0.74) | RXFP1MAPTHDAC1HDAC2HDAC3 | |
| SCHEMBL10598170 | 0.98 | RXFP1 (0.77) | RXFP1MAPTHDAC1HDAC2HDAC3 | |
| SCHEMBL10597136 | 0.98 | RXFP1 (0.77) | RXFP1MAPTHDAC1HDAC2HDAC3 | |
| SCHEMBL10600466 | 0.98 | RXFP1 (0.77) | RXFP1MAPTHDAC1HDAC2HDAC3 | |
| SCHEMBL10595901 | 0.98 | RXFP1 (0.77) | RXFP1MAPTHDAC1HDAC2HDAC3 | |
| SCHEMBL10800242 | 0.98 | RXFP1 (0.77) | RXFP1MAPTHDAC1HDAC2HDAC3 | |
| SCHEMBL10597870 | 0.98 | RXFP1 (0.77) | RXFP1MAPTHDAC1HDAC2HDAC3 | |
| SCHEMBL10598276 | 0.98 | RXFP1 (0.77) | RXFP1MAPTHDAC1HDAC2HDAC3 | |
| SCHEMBL10598573 | 0.98 | RXFP1 (0.77) | RXFP1MAPTHDAC1HDAC2HDAC3 | |
| SCHEMBL10599428 | 0.98 | RXFP1 (0.77) | RXFP1MAPTHDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155524-B1 | -OMEGA-ARYL-ALKYLTHIENYL COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PRODUCTS CONTAINING THESE COMPOUNDS | A. Nattermann & Cie. GmbH (DE) | 1989-04-12 | — | — | EP | disclosed |
| US-4705802-A | Omega-aryl-alkylthienyl-compounds and process for the treatment of chronically inflammatory processes in humans | A. NATTERMANN & CIE GMBH (DE) | 1987-11-10 | — | — | US | disclosed |
| EP-0155524-A1 | -Omega-aryl-alkylthienyl compounds, process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-25 | — | — | EP | disclosed |