SCHEMBL10596409

SCHEMBL10596409

CCCCCCCCOc1ccccc1C(CCCCCCC)Oc1ccc(C(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.56
TSHR P16473 1/20 0.56
PLA2G4B P0C869 6/20 0.55
RARB P10826 3/20 0.53
PPARG P37231 2/20 0.52
PLA2G4A P47712 1/20 0.51
CYSLTR2 Q9NS75 2/20 0.50
CYSLTR1 Q9Y271 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10954885 0.84 TP53 (0.49) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL9325710 0.81 TP53 (0.70) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL6366352 0.78 PPARG (0.53) TSHRPLA2G4BPPARGCYSLTR2CYSLTR1
SCHEMBL6364949 0.78 PPARG (0.53) TSHRPLA2G4BPPARGCYSLTR2CYSLTR1
SCHEMBL6421495 0.78 PPARG (0.53) TSHRPLA2G4BPPARGCYSLTR2CYSLTR1
Benzoic Acid SCHEMBL8014591 0.76 TP53 (0.90) TP53TSHRPLA2G4BRARBPLA2G4A
Benzoic Acid SCHEMBL27635754 0.76 TP53 (0.74) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL18994250 0.76 TP53 (0.54) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL9808804 0.75 RARB (0.70) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL2183384 0.75 TP53 (0.62) TP53TSHRPLA2G4BRARBPLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0342666-A2 Novel biphenyl compounds, method of producing the same as well as liquid crystal compositions and light switching elements each containing the same JAPAN ENERGY CORPORATION (JP) 1989-11-23 EP disclosed