Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | CETP | P11597 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10595780 | 0.93 | TSHR (0.69) | TSHRMAPTRXFP1HDAC3HDAC4 | |
| SCHEMBL4992352 | 0.88 | TSHR (0.66) | TSHRMAPTRXFP1HDAC3HDAC4 | |
| SCHEMBL7379076 | 0.85 | TSHR (0.66) | TSHRMAPTRXFP1HDAC3HDAC4 | |
| 5-Phenylvaleric Acid SCHEMBL503601 | 0.82 | MAPT (0.96) | TSHRMAPTRXFP1HDAC3HDAC4 | |
| SCHEMBL10595932 | 0.81 | TSHR (0.61) | TSHRMAPTRXFP1HDAC3HDAC4 | |
| SCHEMBL2172375 | 0.81 | TSHR (0.70) | TSHRMAPTRXFP1HDAC3HDAC4 | |
| Glutarate SCHEMBL28021756 | 0.80 | HDAC3 (0.65) | TSHRMAPTRXFP1HDAC3HDAC4 | |
| 5-Phenylvaleric Acid SCHEMBL8767462 | 0.80 | MAPT (0.71) | TSHRMAPTRXFP1HDAC3HDAC4 | |
| SCHEMBL1374317 | 0.80 | FOLH1 (0.57) | TSHR | |
| SCHEMBL503837 | 0.80 | MAPT (1.00) | TSHRMAPTRXFP1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0138403-B1 | PROCESS FOR PREPARING PHOSPHINIC ACID INTERMEDIATES | E.R. Squibb & Sons, Inc. (US) | 1989-03-15 | — | — | EP | disclosed |