Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.45 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.45 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.45 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.45 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.42 |
| ▸ | PRKCG | P05129 | 2/20 | 0.42 |
| ▸ | PRKCB | P05771 | 2/20 | 0.42 |
| ▸ | PRKCA | P17252 | 2/20 | 0.42 |
| ▸ | PRKCH | P24723 | 2/20 | 0.42 |
| ▸ | PRKCI | P41743 | 2/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.42 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28995140 | 0.86 | USP2 (0.44) | LPAR1LPAR3LPAR2USP2SPHK1 | |
| SCHEMBL9813404 | 0.85 | USP2 (0.58) | LPAR1LPAR3LPAR6LPAR4LPAR5 | |
| SCHEMBL5764554 | 0.85 | TSHR (0.39) | LPAR1LPAR3LPAR6LPAR4LPAR5 | |
| SCHEMBL10549855 | 0.83 | USP2 (0.63) | LPAR1LPAR3LPAR6LPAR4LPAR5 | |
| SCHEMBL2671655 | 0.83 | USP2 (0.63) | LPAR1LPAR3LPAR6LPAR4LPAR5 | |
| SCHEMBL10566104 | 0.83 | USP2 (0.63) | LPAR1LPAR3LPAR6LPAR4LPAR5 | |
| SCHEMBL10204069 | 0.83 | USP2 (0.63) | LPAR1LPAR3LPAR6LPAR4LPAR5 | |
| SCHEMBL10949767 | 0.83 | USP2 (0.63) | LPAR1LPAR3LPAR6LPAR4LPAR5 | |
| SCHEMBL5796672 | 0.83 | USP2 (0.63) | LPAR1LPAR3LPAR6LPAR4LPAR5 | |
| SCHEMBL10565936 | 0.83 | USP2 (0.63) | LPAR1LPAR3LPAR6LPAR4LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225129-B1 | PHOSPHOLIPID DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1989-05-24 | — | — | EP | disclosed |
| US-4778912-A | ANTITUMOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-10-18 | — | — | US | disclosed |
| EP-0225129-A1 | Phospholipid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-06-10 | — | — | EP | disclosed |