Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10600926 | 1.00 | KCNH2 (0.35) | KCNH2MCHR1DNM1S1PR1 | |
| SCHEMBL29661945 | 0.97 | KCNH2 (0.35) | KCNH2MCHR1DNM1S1PR1 | |
| SCHEMBL29661983 | 0.97 | KCNH2 (0.35) | KCNH2MCHR1DNM1S1PR1 | |
| SCHEMBL29661929 | 0.97 | KCNH2 (0.35) | KCNH2MCHR1DNM1S1PR1 | |
| SCHEMBL29661978 | 0.97 | KCNH2 (0.35) | KCNH2MCHR1DNM1S1PR1 | |
| SCHEMBL29661907 | 0.97 | KCNH2 (0.35) | KCNH2MCHR1DNM1S1PR1 | |
| SCHEMBL10963000 | 0.91 | KCNH2 (0.35) | KCNH2 | |
| SCHEMBL10600723 | 0.91 | KCNH2 (0.35) | KCNH2 | |
| SCHEMBL2729930 | 0.90 | MAPT (0.40) | — | |
| Toluene SCHEMBL28043018 | 0.86 | KCNH2 (0.40) | KCNH2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160620-B1 | METAL DEACTIVATORS | CIBA-GEIGY AG (CH) | 1989-09-13 | — | — | EP | claimed |