Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20985607 | 0.68 | KMT2A (0.38) | CYP19A1TAAR1CA12CA2CA9 | |
| SCHEMBL11044440 | 0.68 | CA12 (0.50) | TAAR1CA12CA2CA9TSHR | |
| SCHEMBL2201285 | 0.68 | CA12 (0.50) | TAAR1CA12CA2CA9TSHR | |
| SCHEMBL31314841 | 0.68 | — | — | |
| SCHEMBL17722158 | 0.67 | CYP1A2 (0.48) | CYP19A1CYP1A2CYP2C19TSHRMAPK1 | |
| SCHEMBL21534 | 0.66 | CA12 (0.48) | TAAR1CA12CA2CA9TSHR | |
| SCHEMBL8529536 | 0.66 | CA12 (0.48) | TAAR1CA12CA2CA9TSHR | |
| SCHEMBL27761885 | 0.66 | CA12 (0.44) | TAAR1CA12CA2CA9TERT | |
| SCHEMBL11145951 | 0.64 | CA12 (0.47) | TAAR1CA12CA2CA9MEN1 | |
| SCHEMBL10283937 | 0.64 | CA12 (0.47) | TAAR1CA12CA2CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160620-B1 | METAL DEACTIVATORS | CIBA-GEIGY AG (CH) | 1989-09-13 | — | — | EP | claimed |