Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.66 |
| ▸ | CNR2 | P34972 | 3/20 | 0.66 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.65 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.65 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.65 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.65 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.65 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.65 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.65 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.65 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.65 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.65 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.65 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.65 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.65 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.65 |
| ▸ | PSMB3 | P49720 | 2/20 | 0.65 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.65 |
| ▸ | PSMA6 | P60900 | 2/20 | 0.65 |
| ▸ | PSMA8 | Q8TAA3 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2678367 | 0.94 | CNR1 (0.74) | CNR1CNR2PSMB11PSMA7PSMB1 | |
| SCHEMBL2678363 | 0.94 | CNR1 (0.74) | CNR1CNR2PSMB11PSMA7PSMB1 | |
| SCHEMBL11195217 | 0.93 | KMT2A (0.56) | CNR1CNR2PSMB11PSMA7PSMB1 | |
| SCHEMBL10603398 | 0.88 | PSMB11 (0.67) | CNR1CNR2PSMB11PSMA7PSMB1 | |
| SCHEMBL452985 | 0.88 | PSMB11 (0.67) | CNR1CNR2PSMB11PSMA7PSMB1 | |
| SCHEMBL452984 | 0.88 | PSMB11 (0.67) | CNR1CNR2PSMB11PSMA7PSMB1 | |
| SCHEMBL15021864 | 0.85 | CNR1 (0.67) | CNR1CNR2PSMB11PSMA7PSMB1 | |
| SCHEMBL17716482 | 0.84 | CNR1 (0.60) | CNR1CNR2PSMB11PSMA7PSMB1 | |
| SCHEMBL11892329 | 0.83 | EGFR (0.56) | CYP1A2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL11892327 | 0.83 | HDAC3 (0.66) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148752-B1 | PROTEASE INHIBITORS | G.D. Searle & Co. (US) | 1989-06-21 | — | — | EP | disclosed |
| US-4551279-A | Protease inhibitors | G. D. SEARLE & CO. (US) | 1985-11-05 | — | — | US | disclosed |
| EP-0148752-A2 | Protease inhibitors | G.D. Searle & Co. (US) | 1985-07-17 | — | — | EP | disclosed |