Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | FASN | P49327 | 1/20 | 0.49 |
| ▸ | TOP1 | P11387 | 3/20 | 0.47 |
| ▸ | PPARD | Q03181 | 5/20 | 0.46 |
| ▸ | PPARA | Q07869 | 5/20 | 0.46 |
| ▸ | FABP4 | P15090 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10603782 | 1.00 | PPARG (0.53) | PPARGALDH1A1MAPTTDP1RECQL | |
| SCHEMBL10606556 | 0.86 | PPARG (0.50) | PPARGALDH1A1MAPTTDP1RECQL | |
| SCHEMBL10606550 | 0.86 | PPARG (0.50) | PPARGALDH1A1MAPTTDP1RECQL | |
| SCHEMBL10608213 | 0.86 | PPARG (0.50) | PPARGALDH1A1MAPTTDP1RECQL | |
| SCHEMBL10608208 | 0.86 | PPARG (0.50) | PPARGALDH1A1MAPTTDP1RECQL | |
| SCHEMBL10606381 | 0.83 | PPARG (0.67) | PPARGALDH1A1MAPTTDP1RECQL | |
| SCHEMBL10606376 | 0.83 | PPARG (0.67) | PPARGALDH1A1MAPTTDP1RECQL | |
| SCHEMBL10603663 | 0.83 | PPARG (0.53) | PPARGALDH1A1MAPTTDP1RECQL | |
| SCHEMBL10603667 | 0.83 | PPARG (0.53) | PPARGALDH1A1MAPTTDP1RECQL | |
| SCHEMBL10607055 | 0.82 | PPARG (0.53) | PPARGALDH1A1MAPTTDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131441-B1 | 5-ALKYLIDENE-2-HALO-4-SUBSTITUTED-2-CYCLOPENTENONE AND PROCESS FOR PRODUCTION THEREOF | TEIJIN LIMITED (JP) | 1989-10-18 | — | — | EP | disclosed |
| US-4689426-A | ANTITUMOR AGENTS, VIRCIDES, BACTERICIDES | TEIJIN LIMITED (JP) | 1987-08-25 | — | — | US | disclosed |
| EP-0131441-A2 | 5-Alkylidene-2-halo-4-substituted-2-cyclopentenone and process for production thereof | TEIJIN LIMITED (JP) | 1985-01-16 | — | — | EP | disclosed |