Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.57 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31027104 | 1.00 | SYK (0.57) | SYKNTSR1POLBL3MBTL1CTSK | |
| SCHEMBL1463134 | 0.95 | POLB (0.58) | SYKNTSR1POLBL3MBTL1CTSK | |
| SCHEMBL7512116 | 0.95 | POLB (0.58) | SYKNTSR1POLBL3MBTL1CTSK | |
| SCHEMBL648574 | 0.95 | POLB (0.58) | SYKNTSR1POLBL3MBTL1CTSK | |
| SCHEMBL29233251 | 0.90 | SYK (0.60) | SYKPOLBCTSKCTSSCTSL | |
| SCHEMBL29813564 | 0.90 | SYK (0.60) | SYKPOLBCTSKCTSSCTSL | |
| SCHEMBL30407619 | 0.90 | SYK (0.60) | SYKPOLBCTSKCTSSCTSL | |
| SCHEMBL17616957 | 0.90 | SYK (0.60) | SYKPOLBCTSKCTSSCTSL | |
| SCHEMBL17616879 | 0.90 | SYK (0.60) | SYKPOLBCTSKCTSSCTSL | |
| SCHEMBL10051906 | 0.89 | SYK (0.54) | SYKNTSR1POLBL3MBTL1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227306-B1 | PEPTIDE IMMUNOSTIMULANTS | PFIZER INC. (US) | 1989-09-13 | — | — | EP | disclosed |
| US-4767743-A | ANTIINFECTION AGENTS | PFIZER INC. (US) | 1988-08-30 | — | — | US | disclosed |
| EP-0227306-A2 | Peptide immunostimulants | PFIZER INC. (US) | 1987-07-01 | — | — | EP | disclosed |