Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GLB1 | P16278 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11316220 | 1.00 | EGFR (0.62) | EGFRNPC1MEN1KMT2ARAB9A | |
| SCHEMBL11316218 | 1.00 | EGFR (0.62) | EGFRNPC1MEN1KMT2ARAB9A | |
| SCHEMBL10624387 | 1.00 | EGFR (0.62) | EGFRNPC1MEN1KMT2ARAB9A | |
| SCHEMBL10624379 | 1.00 | EGFR (0.62) | EGFRNPC1MEN1KMT2ARAB9A | |
| SCHEMBL14690238 | 0.98 | EGFR (0.66) | EGFRNPC1MEN1KMT2ARAB9A | |
| SCHEMBL16153074 | 0.98 | EGFR (0.66) | EGFRNPC1MEN1KMT2ARAB9A | |
| SCHEMBL10939134 | 0.96 | EGFR (0.63) | EGFRNPC1MEN1KMT2ARAB9A | |
| SCHEMBL10939128 | 0.96 | EGFR (0.63) | EGFRNPC1MEN1KMT2ARAB9A | |
| SCHEMBL10939124 | 0.96 | EGFR (0.63) | EGFRNPC1MEN1KMT2ARAB9A | |
| SCHEMBL27889995 | 0.93 | MEN1 (0.59) | EGFRNPC1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144020-B1 | AZODYES AND LIQUID CRYSTALLINE MATERIALS CONTAINING THESE DYES | BASF Aktiengesellschaft (DE) | 1989-05-10 | — | — | EP | disclosed |
| US-4724259-A | Azo dyes and liquid-crystalline materials containing these dyes | BASF AKTIENGESELLSCHAFT (DE) | 1988-02-09 | — | — | US | disclosed |
| EP-0144020-A2 | Azodyes and liquid crystalline materials containing these dyes | BASF Aktiengesellschaft (DE) | 1985-06-12 | — | — | EP | disclosed |
| US-4308163-A | IMPROVING BLACK COLOR OF DICHROIC DYES | GENERAL ELECTRIC COMPANY (US) | 1981-12-29 | — | — | US | disclosed |