Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28904708 | 0.81 | CYP3A4 (0.63) | CYP3A4ALDH1A1SMN1; SMN2ALKBH5KMT2A | |
| SCHEMBL26782451 | 0.79 | CYP3A4 (1.00) | CYP3A4ALDH1A1SMN1; SMN2ALKBH5KMT2A | |
| SCHEMBL10605691 | 0.78 | CYP3A4 (0.63) | CYP3A4ALDH1A1SMN1; SMN2ALKBH5KMT2A | |
| SCHEMBL10607336 | 0.77 | CYP3A4 (0.75) | CYP3A4ALDH1A1SMN1; SMN2ALKBH5KMT2A | |
| SCHEMBL1043816 | 0.77 | CYP3A4 (0.75) | CYP3A4ALDH1A1SMN1; SMN2ALKBH5KMT2A | |
| SCHEMBL10607082 | 0.77 | CYP3A4 (0.75) | CYP3A4ALDH1A1SMN1; SMN2ALKBH5KMT2A | |
| SCHEMBL10608362 | 0.77 | CYP3A4 (0.75) | CYP3A4ALDH1A1SMN1; SMN2ALKBH5KMT2A | |
| SCHEMBL6667574 | 0.77 | CYP3A4 (0.75) | CYP3A4ALDH1A1SMN1; SMN2ALKBH5KMT2A | |
| SCHEMBL2798211 | 0.76 | TAAR1 (0.53) | CYP3A4SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10605945 | 0.76 | CYP3A4 (0.73) | CYP3A4ALDH1A1SMN1; SMN2ALKBH5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219371-B1 | ANISOLE DERIVATIVES | MITSUBISHI KASEI CORPORATION (JP) | 1989-11-08 | — | — | EP | claimed |
| US-4746747-A | Anisole derivatives | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1988-05-24 | — | — | US | claimed |
| EP-0219371-A2 | Anisole derivatives | MITSUBISHI KASEI CORPORATION (JP) | 1987-04-22 | — | — | EP | claimed |
| EP-0219371-B1 | ANISOLE DERIVATIVES | MITSUBISHI KASEI CORPORATION (JP) | 1989-11-08 | — | — | EP | disclosed |
| US-4746747-A | Anisole derivatives | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1988-05-24 | — | — | US | disclosed |
| EP-0219371-A2 | Anisole derivatives | MITSUBISHI KASEI CORPORATION (JP) | 1987-04-22 | — | — | EP | disclosed |