Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RARA | P10276 | 2/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10554650 | 1.00 | RARB (0.56) | RARBRAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL10563354 | 1.00 | RARB (0.56) | RARBRAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL10560171 | 1.00 | RARB (0.56) | RARBRAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL10557647 | 1.00 | RARB (0.56) | RARBRAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL10559342 | 1.00 | RARB (0.56) | RARBRAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL10558682 | 1.00 | RARB (0.56) | RARBRAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL10556976 | 1.00 | RARB (0.56) | RARBRAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL10560949 | 1.00 | RARB (0.56) | RARBRAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL10558513 | 1.00 | RARB (0.56) | RARBRAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL10556054 | 1.00 | RARB (0.56) | RARBRAB9AMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126949-B1 | FLUORINE-CONTAINING PYRIMIDINE DERIVATIVES | MERCK PATENT GmbH (DE) | 1989-09-27 | — | — | EP | disclosed |