Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.52 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.52 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MAOA | P21397 | 6/20 | 0.46 |
| ▸ | FGR | P09769 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.46 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | RECQL | P46063 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6904553 | 0.83 | IDO1 (0.59) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL8845047 | 0.79 | DNMT1 (0.54) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL6650819 | 0.78 | MEN1 (0.55) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL9132597 | 0.75 | IDO1 (0.41) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL6905734 | 0.74 | CYP1A1 (0.56) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL308115 | 0.73 | ADORA2A (0.76) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL3418850 | 0.73 | MEN1 (0.55) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL22283344 | 0.73 | TTR (0.36) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL2254507 | 0.73 | CYP1A1 (0.59) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL10618703 | 0.73 | CYP1A1 (0.59) | IDO1DNMT1DNMT3LDNMT3AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170190-B1 | METHOD FOR PRODUCTION OF FLUORINATED QUINONES | Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) | 1989-12-06 | — | — | EP | disclosed |
| US-4689179-A | FLUORINATION OF CHLORINATED ANHYDRIDES OR QUINONES; CROWN ETHER CATALYST, PHASE TRANSFER | NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) | 1987-08-25 | — | — | US | disclosed |
| EP-0170190-A2 | Method for production of fluorinated quinones | Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) | 1986-02-05 | — | — | EP | disclosed |