Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 12/20 | 0.80 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.80 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.80 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.80 |
| ▸ | LMNA | P02545 | 1/20 | 0.80 |
| ▸ | MAPT | P10636 | 1/20 | 0.80 |
| ▸ | BLM | P54132 | 1/20 | 0.80 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.80 |
| ▸ | HTR7 | P34969 | 1/20 | 0.79 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.79 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6663117 | 1.00 | ADORA1 (0.80) | ADORA1ADORA3ADORA2AADORA2BHIF1A | |
| SCHEMBL14906550 | 1.00 | ADORA1 (0.80) | ADORA1ADORA3ADORA2AADORA2BHIF1A | |
| SCHEMBL14903066 | 0.90 | ADORA1 (0.84) | ADORA1ADORA3ADORA2AADORA2BHIF1A | |
| SCHEMBL12319037 | 0.90 | ADORA1 (0.78) | ADORA1ADORA3ADORA2AADORA2BHIF1A | |
| SCHEMBL10608249 | 0.89 | ADORA1 (1.00) | ADORA1ADORA3ADORA2AADORA2BHIF1A | |
| SCHEMBL21033426 | 0.89 | ADORA1 (1.00) | ADORA1ADORA3ADORA2AADORA2BHIF1A | |
| SCHEMBL12265125 | 0.89 | ADORA1 (1.00) | ADORA1ADORA3ADORA2AADORA2BHIF1A | |
| SCHEMBL2248193 | 0.89 | ADORA1 (1.00) | ADORA1ADORA3ADORA2AADORA2BHIF1A | |
| SCHEMBL10529743 | 0.89 | ADORA1 (1.00) | ADORA1ADORA3ADORA2AADORA2BHIF1A | |
| SCHEMBL13276118 | 0.89 | ADORA1 (1.00) | ADORA1ADORA3ADORA2AADORA2BHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0181128-B1 | N6-BICYCLOADENOSINES | WARNER-LAMBERT COMPANY (US) | 1989-10-04 | — | — | EP | disclosed |