Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 7/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.48 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488349 | 0.79 | MEN1 (0.60) | CARM1PRMT6PRMT8MEN1KMT2A | |
| SCHEMBL4331083 | 0.79 | MEN1 (0.60) | CARM1PRMT6PRMT8MEN1KMT2A | |
| SCHEMBL4333351 | 0.79 | MEN1 (0.60) | CARM1PRMT6PRMT8MEN1KMT2A | |
| SCHEMBL16181815 | 0.78 | MEN1 (0.64) | CARM1PRMT6MEN1KMT2AMAPT | |
| SCHEMBL15314029 | 0.77 | MEN1 (0.44) | CARM1PRMT6PRMT8MEN1KMT2A | |
| SCHEMBL15314033 | 0.75 | KMT2A (0.43) | CARM1PRMT6PRMT8MEN1KMT2A | |
| SCHEMBL14878580 | 0.75 | MEN1 (0.48) | CARM1PRMT6PRMT8MEN1KMT2A | |
| SCHEMBL3488699 | 0.74 | MAPT (0.60) | CARM1PRMT6PRMT8MEN1KMT2A | |
| SCHEMBL5825413 | 0.73 | MEN1 (0.46) | CARM1PRMT6PRMT8MEN1KMT2A | |
| SCHEMBL3271095 | 0.73 | HRH3 (0.46) | CARM1PRMT6PRMT8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4783535-A | Chemical intermediates in the preparation of aromatic-1,4-oxazepinones and thiones | A. H. ROBINS COMPANY, INCORPORATED (US) | 1988-11-08 | — | — | US | disclosed |
| US-4610819-A | Process for the preparation of aromatic-1,4-oxazepinones and thiones | A. H. ROBINS COMPANY, INC. (US) | 1986-09-09 | — | — | US | disclosed |
| EP-0175570-A2 | Process for the preparation of aromatic-1,4-oxazepinones and thiones | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1986-03-26 | — | — | EP | disclosed |