Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 6/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10613179 | 0.99 | KDM4E (0.38) | KDM4EPDE4APDE4DPDE4BPDE4C | |
| SCHEMBL10609336 | 0.96 | KDM4E (0.40) | KDM4EPDE4APDE4D | |
| SCHEMBL10608760 | 0.89 | KDM4E (0.39) | KDM4E | |
| SCHEMBL10611947 | 0.89 | KDM4E (0.35) | KDM4E | |
| SCHEMBL10608680 | 0.87 | KDM4E (0.42) | KDM4E | |
| SCHEMBL10613231 | 0.83 | HTR2C (0.36) | KDM4EPDE4APDE4DPDE4BPDE4C | |
| SCHEMBL10610513 | 0.82 | PDE4D (0.36) | KDM4EPDE4APDE4DPDE4B | |
| SCHEMBL10610326 | 0.80 | NOX1 (0.38) | KDM4EKMT2A | |
| SCHEMBL10610280 | 0.80 | PDK2 (0.34) | — | |
| SCHEMBL10609472 | 0.80 | KDM4E (0.36) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271550-A1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AND COMPOSITIONS CONTAINING THEM | ALKALOIDA VEGYéSZETI GYáR (HU) | 1988-06-22 | — | — | EP | disclosed |
| WO-1988000197-A1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AND COMPOSITIONS CONTAINING THEM | ALKALOIDA VEGYE^´SZETI GYA^´R (HU) | 1988-01-14 | — | — | WO | disclosed |