Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 8/20 | 0.34 |
| ▸ | CNR1 | P21554 | 6/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10609580 | 0.97 | CNR2 (0.36) | KDM4ECNR2CNR1HTR1AHTR2A | |
| SCHEMBL10611884 | 0.96 | CNR2 (0.37) | KDM4ECNR2CNR1HTR1AHTR2A | |
| SCHEMBL10610467 | 0.96 | CNR2 (0.37) | KDM4ECNR2CNR1HTR1AHTR2A | |
| SCHEMBL10608707 | 0.96 | CNR2 (0.37) | KDM4ECNR2CNR1HTR1AHTR2A | |
| SCHEMBL10611366 | 0.94 | KDM4E (0.35) | KDM4ECNR2CNR1 | |
| SCHEMBL10612536 | 0.90 | KDM4E (0.36) | KDM4ECNR2CNR1 | |
| SCHEMBL10609472 | 0.90 | KDM4E (0.36) | KDM4ECNR2CNR1 | |
| SCHEMBL10608680 | 0.88 | KDM4E (0.42) | KDM4E | |
| SCHEMBL10612523 | 0.85 | KDM4E (0.32) | KDM4ECNR2CNR1 | |
| SCHEMBL10612426 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271550-A1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AND COMPOSITIONS CONTAINING THEM | ALKALOIDA VEGYéSZETI GYáR (HU) | 1988-06-22 | — | — | EP | disclosed |
| WO-1988000197-A1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AND COMPOSITIONS CONTAINING THEM | ALKALOIDA VEGYE^´SZETI GYA^´R (HU) | 1988-01-14 | — | — | WO | disclosed |