Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCNA | P12004 | 13/20 | 0.72 |
| ▸ | THRB | P10828 | 7/20 | 0.64 |
| ▸ | THRA | P10827 | 5/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14485275 | 0.84 | PCNA (1.00) | PCNATHRBTHRAPOLBHIF1A | |
| SCHEMBL16124470 | 0.82 | PCNA (0.82) | PCNATHRBTHRAPOLBHIF1A | |
| SCHEMBL16124429 | 0.81 | PCNA (0.66) | PCNATHRBTHRAPOLBHIF1A | |
| SCHEMBL16124433 | 0.80 | PCNA (0.80) | PCNATHRBTHRAPOLBHIF1A | |
| Thyropropic Acid SCHEMBL310201 | 0.79 | PCNA (1.00) | PCNATHRBTHRAPOLBHIF1A | |
| SCHEMBL16124432 | 0.78 | PCNA (0.76) | PCNATHRBTHRAPOLBHIF1A | |
| SCHEMBL16124441 | 0.78 | PCNA (1.00) | PCNATHRBTHRAPOLBHIF1A | |
| SCHEMBL10609147 | 0.78 | PCNA (0.55) | PCNATHRBTHRAPOLBHIF1A | |
| SCHEMBL16124450 | 0.77 | PCNA (0.86) | PCNATHRBTHRAPOLBHIF1A | |
| SCHEMBL13886708 | 0.77 | PCNA (0.59) | PCNATHRBTHRAPOLBHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4741897-A | Thyroxine analogs and reagents for thyroid hormone assays | BAXTER TRAVENOL (US) | 1988-05-03 | — | — | US | disclosed |