Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 19/20 | 0.64 |
| ▸ | LY96 | Q9Y6Y9 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6567651 | 0.95 | TLR4 (0.69) | TLR4LY96 | |
| SCHEMBL6567647 | 0.95 | TLR4 (0.69) | TLR4LY96 | |
| SCHEMBL3928509 | 0.92 | TLR4 (0.69) | TLR4LY96 | |
| SCHEMBL3937496 | 0.92 | TLR4 (0.69) | TLR4LY96 | |
| SCHEMBL3933640 | 0.92 | TLR4 (0.64) | TLR4LY96 | |
| SCHEMBL3925341 | 0.92 | TLR4 (0.69) | TLR4LY96 | |
| SCHEMBL3925303 | 0.92 | TLR4 (0.64) | TLR4LY96 | |
| SCHEMBL3938094 | 0.92 | TLR4 (0.69) | TLR4LY96 | |
| SCHEMBL7502609 | 0.92 | TLR4 (0.69) | TLR4LY96 | |
| SCHEMBL3930073 | 0.92 | TLR4 (0.69) | TLR4LY96 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4746742-A | IMMUNOLOGY, ANTI-TUMOR | TOHO YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1988-05-24 | — | — | US | disclosed |
| EP-0224260-A2 | Analogs of nonreducing monosaccharide moiety of lipid A | Toho Yakuhin Kogyo Kabushiki Kaisha (JP) | 1987-06-03 | — | — | EP | disclosed |