Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234197 | 0.68 | — | — | |
| SCHEMBL5703315 | 0.68 | CETP (0.30) | — | |
| SCHEMBL5703337 | 0.68 | CETP (0.30) | — | |
| SCHEMBL284814 | 0.68 | CETP (0.30) | — | |
| SCHEMBL5703325 | 0.66 | — | — | |
| SCHEMBL17465686 | 0.66 | — | — | |
| SCHEMBL5703328 | 0.66 | — | — | |
| SCHEMBL5703284 | 0.66 | — | — | |
| SCHEMBL9734522 | 0.65 | DPP4 (0.30) | — | |
| SCHEMBL233787 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4296029-A | Process for preparing hexahydroazepine, piperidine and pyrrolidine derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1981-10-20 | — | — | US | claimed |
| US-4760158-A | Cyclic halonitriles | JOHN WYETH & BROTHER LIMITED (GB) | 1988-07-26 | — | — | US | disclosed |
| US-4593111-A | Silyl isothiocyanates | JOHN WYETH & BROTHER LTD. (GB) | 1986-06-03 | — | — | US | disclosed |
| US-4577022-A | Silyl compounds | JOHN WYETH & BROTHER, LTD. (GB) | 1986-03-18 | — | — | US | disclosed |
| US-4539406-A | REACTION OF A SILYL COMPOUND WITH A METAL TETRAHYDROQUINOLINE, ALCOHOLYSIS | JOHN WYETH & BROTHER LIMITED (GB) | 1985-09-03 | — | — | US | disclosed |
| US-4529798-A | Reacting the correcponding lithium, sodium, potassium or magnesium halide compound with a aminonitrile compound | JOHN WYETH & BROTHER LIMITED (GB) | 1985-07-16 | — | — | US | disclosed |
| US-4526970-A | Reacting tetrahydroquinoline sodium, potassium, lithium, or magnesium compound with silyl compound, subjecting product to hydrolysis or alcoholysis | JOHN WYETH & BROTHER LIMITED (GB) | 1985-07-02 | — | — | US | disclosed |
| EP-0054384-B1 | PROCESS FOR PREPARING PYRIDINE DERIVATIVES | JOHN WYETH & BROTHER LIMITED (GB) | 1984-06-27 | — | — | EP | disclosed |
| EP-0021552-B1 | HEXAHYDROAZEPINE, PIPERIDINE AND PYRROLIDINE DERIVATIVES AND PROCESSES FOR PREPARING THEM | JOHN WYETH & BROTHER LIMITED (GB) | 1983-01-26 | — | — | EP | disclosed |
| EP-0054384-A1 | Process for preparing pyridine derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1982-06-23 | — | — | EP | disclosed |
| US-4296029-A | Process for preparing hexahydroazepine, piperidine and pyrrolidine derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1981-10-20 | — | — | US | disclosed |
| EP-0021772-A1 | Method of preparing 2-oxo- and 2-unsubstituted-hexahydroazepine derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1981-01-07 | — | — | EP | disclosed |
| EP-0021552-A1 | Hexahydroazepine, piperidine and pyrrolidine derivatives and processes for preparing them | JOHN WYETH & BROTHER LIMITED (GB) | 1981-01-07 | — | — | EP | disclosed |
| US-4197241-A | Hexahydroazepine, piperidine and pyrrolidine derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1980-04-08 | — | — | US | disclosed |
| EP-0003253-A1 | Hexahydroazepine, piperidine and pyrrolidine derivatives and processes for making and using them | JOHN WYETH & BROTHER LIMITED (GB) | 1979-08-08 | — | — | EP | disclosed |
| US-4163785-A | ANTIHISTAMINES, ANTIANAPHYLATIC | HEXACHIMIE (FR) | 1979-08-07 | — | — | US | disclosed |