Formamide

Formamide

SCHEMBL10616630

C=CCc1ccc2ccccc2c1S(=O)(=O)O.NC=O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.40
ERN1 O75460 1/20 0.36
SLC2A1 P11166 4/20 0.36
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
HPGD P15428 1/20 0.34
POLB P06746 1/20 0.33
CA2 P00918 1/20 0.33
RAB9A P51151 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PKM P14618 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL371329 0.94 CYP2D6 (0.43) CYP2D6ERN1SLC2A1MEN1KMT2A
Rubidium SCHEMBL18141746 0.93 CYP2D6 (0.42) CYP2D6ERN1SLC2A1MEN1KMT2A
SCHEMBL287155 0.93 CYP2D6 (0.42) CYP2D6ERN1SLC2A1MEN1KMT2A
Formaldehyde SCHEMBL3295297 0.93 CYP2D6 (0.42) CYP2D6ERN1SLC2A1MEN1KMT2A
SCHEMBL18141781 0.93 CYP2D6 (0.42) CYP2D6ERN1SLC2A1MEN1KMT2A
Ammonia Solution, Strong SCHEMBL18140081 0.93 CYP2D6 (0.42) CYP2D6ERN1SLC2A1MEN1KMT2A
SCHEMBL18140008 0.93 CYP2D6 (0.42) CYP2D6ERN1SLC2A1MEN1KMT2A
Formaldehyde SCHEMBL8649899 0.92 CYP2D6 (0.41) CYP2D6ERN1SLC2A1MEN1KMT2A
SCHEMBL18139297 0.87 HPRT1 (0.40) CYP2D6ERN1SLC2A1MEN1KMT2A
SCHEMBL9407396 0.86 CYP2D6 (0.41) CYP2D6MEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63258991-A None JP disclosed
JP-S63258991-A ADDITIVE FOR HIGH-CONCENTRATION COAL-WATER SLURRY HAVING LONG FIFE DAI ICHI KOGYO SEIYAKU CO LTD 1988-10-26 JP disclosed