Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 8/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 8/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11723868 | 0.85 | MEN1 (0.63) | PTGER4PTGER2PTGER3MEN1KMT2A | |
| SCHEMBL11250679 | 0.84 | PTGER2 (0.40) | PTGER4PTGER2PTGER3MEN1KMT2A | |
| SCHEMBL11250676 | 0.84 | PTGER2 (0.40) | PTGER4PTGER2PTGER3MEN1KMT2A | |
| SCHEMBL11863993 | 0.84 | MEN1 (0.61) | PTGER4PTGER2PTGER3MEN1KMT2A | |
| SCHEMBL11864006 | 0.84 | MEN1 (0.61) | PTGER4PTGER2PTGER3MEN1KMT2A | |
| SCHEMBL11864001 | 0.84 | MEN1 (0.61) | PTGER4PTGER2PTGER3MEN1KMT2A | |
| SCHEMBL28339789 | 0.81 | PTGER4 (0.48) | PTGER4PTGER2PTGER3MEN1KMT2A | |
| SCHEMBL11251902 | 0.81 | PTGER2 (0.52) | PTGER4PTGER2PTGER3MEN1KMT2A | |
| SCHEMBL11044232 | 0.80 | PTGIR (0.58) | PTGER4PTGER2PTGER3MEN1KMT2A | |
| SCHEMBL10621611 | 0.80 | PTGIR (0.58) | PTGER4PTGER2PTGER3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766147-A | ANTITUMOR AGENTS | TEIJIN LIMITED (JP) | 1988-08-23 | — | — | US | disclosed |
| EP-0106576-B1 | NOVEL 5-MEMBERED CYCLIC COMPOUNDS, PROCESS FOR THE PRODUCTION THEREOF, AND PHARMACEUTICAL USE THEREOF | TEIJIN LIMITED (JP) | 1988-03-09 | — | — | EP | disclosed |
| EP-0106576-A2 | Novel 5-membered cyclic compounds, process for the production thereof, and pharmaceutical use thereof | TEIJIN LIMITED (JP) | 1984-04-25 | — | — | EP | disclosed |