⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL568783 | 0.77 | — | — | |
| SCHEMBL14342573 | 0.73 | — | — | |
| SCHEMBL25429060 | 0.70 | — | — | |
| SCHEMBL25431722 | 0.70 | — | — | |
| SCHEMBL18568233 | 0.69 | — | — | |
| SCHEMBL1197050 | 0.69 | — | — | |
| SCHEMBL28655162 | 0.69 | — | — | |
| SCHEMBL15374805 | 0.67 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL1503 | 0.67 | — | — | |
| SCHEMBL29150915 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151640-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023092149-A1 | HETEROCYCLIC SUBSTITUTED 1,3,4-THIADIAZOLE AND PYRIDAZINE COMPOUNDS AND METHODS OF USING THE SAME | RGENTA THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |
| US-4732887-A | RESIN IN VOIDS FOR CHROMATOGRAPHY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1988-03-22 | — | — | US | disclosed |
| US-4093570-A | CROSSLINKABLE, MIXED ORGANIC MEDIUM; | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) | 1978-06-06 | — | — | US | disclosed |