Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | BLM | P54132 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NSD2 | O96028 | 2/20 | 0.55 |
| ▸ | MTOR | P42345 | 2/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.55 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.55 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.55 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10633579 | 0.90 | MEN1 (0.52) | MEN1KMT2ABLMLMNAMAPK1 | |
| SCHEMBL10702797 | 0.87 | MEN1 (0.50) | MEN1KMT2ABLMLMNAMAPK1 | |
| SCHEMBL10629098 | 0.87 | MEN1 (0.50) | MEN1KMT2ABLMLMNAMAPK1 | |
| SCHEMBL10706097 | 0.84 | MEN1 (0.52) | MEN1KMT2ABLMLMNAMAPK1 | |
| SCHEMBL10627603 | 0.83 | KMT2A (0.51) | MEN1KMT2ABLMLMNAMAPK1 | |
| SCHEMBL10627498 | 0.83 | MEN1 (0.51) | MEN1KMT2ABLMLMNAMAPK1 | |
| SCHEMBL9212960 | 0.83 | KMT2A (0.51) | MEN1KMT2ABLMLMNAMAPK1 | |
| SCHEMBL10633606 | 0.82 | MEN1 (0.45) | MEN1KMT2ABLMLMNAMAPK1 | |
| SCHEMBL9207933 | 0.82 | KMT2A (0.50) | MEN1KMT2ABLMLMNAMAPK1 | |
| SCHEMBL10633510 | 0.82 | KMT2A (0.50) | MEN1KMT2ABLMLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732970-A | Antitumor amino acid and peptide derivatives of 1,4-bis(aminoalkyl and hydroxy-aminoalkyl)amino)-5,8-dihydroxyanthraquinones | AMERICAN CYANAMID COMPANY (US) | 1988-03-22 | — | — | US | disclosed |