Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10350027 | 0.87 | DPP4 (0.93) | DPP4F2LMNAADRA2AADRA2C | |
| SCHEMBL2067094 | 0.84 | DPP4 (1.00) | DPP4F2LMNAADRA2AADRA2C | |
| SCHEMBL150159 | 0.84 | DPP4 (1.00) | DPP4F2LMNAADRA2AADRA2C | |
| SCHEMBL851654 | 0.84 | DPP4 (1.00) | DPP4F2LMNAADRA2AADRA2C | |
| SCHEMBL239938 | 0.84 | DPP4 (1.00) | DPP4F2LMNAADRA2AADRA2C | |
| SCHEMBL1878642 | 0.84 | DPP4 (1.00) | DPP4F2LMNAADRA2AADRA2C | |
| SCHEMBL644767 | 0.84 | DPP4 (1.00) | DPP4F2LMNAADRA2AADRA2C | |
| SCHEMBL1614122 | 0.83 | DPP4 (0.67) | DPP4CYP2D6SRCF2LMNA | |
| SCHEMBL1614121 | 0.83 | DPP4 (0.67) | DPP4CYP2D6SRCF2LMNA | |
| Oxalic Acid SCHEMBL10874731 | 0.81 | DPP4 (0.64) | DPP4CYP2D6SRCF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4730068-A | SPECIAL EFFECT ON BREAST CANCER | ASTA-WERKE AKTIENGESELLSCHAFT (DE) | 1988-03-08 | — | — | US | disclosed |
| US-4598091-A | (1,2-diphenyl)-ethylenediamine)-platinum (II) complex compounds | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1986-07-01 | — | — | US | disclosed |