Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.53 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.53 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10638571 | 1.00 | PPARA (0.53) | PPARATSHRCYP2C8CYP2C9TDP1 | |
| SCHEMBL10635715 | 0.90 | PPARA (0.55) | PPARATSHRCYP2C8CYP2C9TDP1 | |
| SCHEMBL10635736 | 0.90 | PPARA (0.55) | PPARATSHRCYP2C8CYP2C9TDP1 | |
| SCHEMBL10639807 | 0.86 | TSHR (0.53) | PPARATSHRCYP2C8CYP2C9TDP1 | |
| SCHEMBL10639817 | 0.86 | TSHR (0.53) | PPARATSHRCYP2C8CYP2C9TDP1 | |
| SCHEMBL10638407 | 0.85 | PPARA (0.56) | PPARATSHRCYP2C8CYP2C9TDP1 | |
| SCHEMBL10638404 | 0.85 | PPARA (0.56) | PPARATSHRCYP2C8CYP2C9TDP1 | |
| SCHEMBL10640335 | 0.85 | PPARA (0.52) | PPARATSHRCYP2C8CYP2C9TDP1 | |
| SCHEMBL10640327 | 0.85 | PPARA (0.52) | PPARATSHRCYP2C8CYP2C9TDP1 | |
| SCHEMBL10638693 | 0.84 | PPARA (0.51) | PPARATSHRCYP2C8CYP2C9TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0134337-B1 | SUBSTITUTED 2,2-DIMETHYL-5-PHENOXYPENTANOIC ACID BENZAMIDES AND THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1988-01-07 | — | — | EP | claimed |