SCHEMBL10639673

SCHEMBL10639673

CCCCCCCCSCC(C)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.55
GMNN O75496 1/20 0.55
TP53 P04637 1/20 0.55
POLB P06746 1/20 0.55
THRB P10828 1/20 0.55
CYP2C9 P11712 1/20 0.55
BLM P54132 1/20 0.55
HSD17B10 Q99714 1/20 0.55
ACE2 Q9BYF1 1/20 0.52
CES2 O00748 3/20 0.50
EPHX1 P07099 1/20 0.46
FAAH O00519 4/20 0.44
CES1 P23141 4/20 0.44
PLA2G6 O60733 1/20 0.44
GPR84 Q9NQS5 3/20 0.42
FFAR1 O14842 1/20 0.42
LCK P06239 1/20 0.41
PPARD Q03181 1/20 0.41
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9106808 1.00 MAPT (0.55) MAPTGMNNTP53POLBTHRB
SCHEMBL9355083 1.00 MAPT (0.55) MAPTGMNNTP53POLBTHRB
SCHEMBL9851243 1.00 MAPT (0.55) MAPTGMNNTP53POLBTHRB
SCHEMBL11089311 1.00 MAPT (0.55) MAPTGMNNTP53POLBTHRB
SCHEMBL7167169 0.98 MAPT (0.52) MAPTGMNNTP53POLBTHRB
SCHEMBL9734941 0.92 ACE2 (0.46) MAPTGMNNTP53POLBTHRB
SCHEMBL9074387 0.90 ACE2 (0.47) MAPTGMNNTP53POLBTHRB
SCHEMBL10667103 0.90 GMNN (0.46) MAPTGMNNTP53POLBTHRB
SCHEMBL11660304 0.87 ACE2 (0.45) MAPTGMNNTP53POLBTHRB
SCHEMBL11661027 0.87 ACE2 (0.45) MAPTGMNNTP53POLBTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116947951-A Compound with STING channel activating function and application thereof 成都威斯津生物医药科技有限公司 2023-10-27 CN claimed
CN-116947951-A Compound with STING channel activating function and application thereof 成都威斯津生物医药科技有限公司 2023-10-27 CN disclosed
EP-0259465-A1 PROCESS FOR PREPARING OPTICALLY-ACTIVE 3-ACYLTHIO-2-METHYLPROPIONIC ACID DERIVATIVES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1988-03-16 EP disclosed
WO-1987005328-A1 PROCESS FOR PREPARING OPTICALLY-ACTIVE 3-ACYLTHIO-2-METHYLPROPIONIC ACID DERIVATIVES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1987-09-11 WO disclosed
US-4239803-A CONTAINING ALKYLTHIOALKYLENECAROXYLIC ACID ESTER OF A POLYCARBOCYCC POLYHYDRIC PHENOL ARGUS CHEMICAL CORPORATION (US) 1980-12-16 US disclosed
US-4089911-A POLYVINYL CHLORIDE BLEND, METAL ALKYLTHIOCARBOXYLATE THERMAL STABILIZER KAO SOAP CO., LTD. (JA) 1978-05-16 US disclosed