Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1100760 | 0.94 | TSHR (0.56) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL10798402 | 0.92 | TSHR (0.54) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL5851712 | 0.92 | TSHR (0.54) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL12659255 | 0.92 | TSHR (0.54) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL5143791 | 0.86 | — | — | |
| SCHEMBL17208538 | 0.81 | TSHR (0.42) | TSHRLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL7772507 | 0.81 | TSHR (0.56) | TSHRLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL14942516 | 0.80 | TSHR (0.45) | TSHRLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL27799112 | 0.79 | TSHR (0.54) | TSHRLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL7276581 | 0.79 | CYP1A2 (0.53) | TSHRALDH1A1KMT2AEPHX2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0137145-B1 | NEW CAMPTOTHECIN DERIVATIVES AND PROCESS FOR PREPARING SAME | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1988-04-27 | — | — | EP | disclosed |