Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10636638 | 1.00 | MAPT (0.37) | MAPTRAB9AHSD17B10KDM4EPOLB | |
| SCHEMBL10639927 | 0.80 | HSD17B10 (0.44) | MAPTRAB9AHSD17B10KDM4EPOLB | |
| SCHEMBL10639925 | 0.80 | HSD17B10 (0.44) | MAPTRAB9AHSD17B10KDM4EPOLB | |
| SCHEMBL6019014 | 0.80 | HSD17B10 (0.44) | MAPTRAB9AHSD17B10KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL10636650 | 0.78 | HSD17B10 (0.43) | MAPTRAB9AHSD17B10KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL10639897 | 0.78 | HSD17B10 (0.43) | MAPTRAB9AHSD17B10KDM4EPOLB | |
| SCHEMBL536125 | 0.71 | — | — | |
| SCHEMBL14851716 | 0.69 | — | — | |
| SCHEMBL14963076 | 0.68 | CYP1A2 (0.50) | HSD17B10KDM4EPOLBSMN1; SMN2TDP1 | |
| SCHEMBL9076943 | 0.66 | TDP1 (0.56) | HSD17B10KDM4EPOLBTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4794109-A | 6-hydroxy-lower alkylpenem compounds, pharmaceutical preparations that contain these compounds, and the use of the latter | CIBA-GEIGY CORPORATION (US) | 1988-12-27 | — | — | US | disclosed |