Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 11/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10640022 | 0.94 | OPRL1 (0.56) | OPRL1OPRM1OPRD1OPRK1CYP2D6 | |
| SCHEMBL10643178 | 0.85 | OPRL1 (0.55) | OPRL1OPRM1OPRD1OPRK1CYP2D6 | |
| SCHEMBL10639858 | 0.83 | OPRL1 (0.63) | OPRL1OPRM1OPRD1OPRK1CYP2D6 | |
| SCHEMBL10640033 | 0.78 | OPRL1 (0.53) | OPRL1OPRM1OPRD1OPRK1CYP2D6 | |
| SCHEMBL1681737 | 0.77 | OPRL1 (0.56) | OPRL1OPRM1OPRD1OPRK1CYP2D6 | |
| SCHEMBL1681920 | 0.77 | OPRL1 (0.56) | OPRL1OPRM1OPRD1OPRK1CYP2D6 | |
| SCHEMBL1681741 | 0.77 | OPRL1 (0.56) | OPRL1OPRM1OPRD1OPRK1CYP2D6 | |
| SCHEMBL13741191 | 0.77 | CYP2D6 (0.35) | OPRL1OPRM1OPRD1OPRK1CYP2D6 | |
| Hydrochloric Acid SCHEMBL1682087 | 0.76 | OPRL1 (0.55) | OPRL1OPRM1OPRD1OPRK1CYP2D6 | |
| Hydrochloric Acid SCHEMBL1681488 | 0.76 | OPRL1 (0.55) | OPRL1OPRM1OPRD1OPRK1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295833-A1 | Aromatic-Spiropiperidine oxazepinones (and thiones) | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1988-12-21 | — | — | EP | disclosed |
| US-4746655-A | ANTIHISTAMINES | A. H. ROBINS COMPANY, INCORPORATED (US) | 1988-05-24 | — | — | US | disclosed |