Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10637722 | 0.96 | HMGCR (0.78) | HMGCR | |
| SCHEMBL10636920 | 0.93 | HMGCR (0.84) | HMGCR | |
| SCHEMBL10634559 | 0.83 | HMGCR (0.51) | HMGCR | |
| SCHEMBL10564879 | 0.83 | HMGCR (0.84) | HMGCR | |
| SCHEMBL10634659 | 0.80 | HMGCR (0.71) | HMGCR | |
| SCHEMBL10640263 | 0.80 | HMGCR (0.63) | HMGCR | |
| SCHEMBL10640255 | 0.79 | HMGCR (0.54) | HMGCR | |
| SCHEMBL10640271 | 0.79 | HMGCR (0.71) | HMGCR | |
| SCHEMBL10640278 | 0.79 | HMGCR (0.71) | HMGCR | |
| SCHEMBL6950716 | 0.76 | HMGCR (0.61) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4751229-A | Treating fungal infections with substituted-(6-(tetrahydro-4-hydroxy-2-oxo-2H-pyran-2-yl)ethyl)- or ethenyl)pyrazoles | WARNER-LAMBERT COMPANY (US) | 1988-06-14 | — | — | US | disclosed |