Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.64 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.64 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.64 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 2/20 | 0.46 |
| ▸ | FNTB | P49356 | 2/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748629 | 0.80 | CYP19A1 (0.62) | CYP19A1CYP11B1CYP11B2TBXAS1CYP2A6 | |
| SCHEMBL771716 | 0.79 | CYP11B1 (1.00) | CYP19A1CYP11B1CYP11B2TBXAS1CYP2A6 | |
| SCHEMBL6991458 | 0.78 | CYP11B1 (0.61) | CYP19A1CYP11B1CYP11B2TBXAS1CYP2A6 | |
| SCHEMBL10856339 | 0.78 | CYP19A1 (0.67) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| Hydrochloric Acid SCHEMBL8307735 | 0.77 | CYP11B1 (0.97) | CYP19A1CYP11B1CYP11B2TBXAS1CYP2A6 | |
| Hydrazine SCHEMBL28019549 | 0.76 | CYP11B1 (0.94) | CYP19A1CYP11B1CYP11B2TBXAS1CYP2A6 | |
| SCHEMBL10583639 | 0.74 | CYP11B1 (0.56) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL10583642 | 0.74 | CYP11B1 (0.56) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| Hydrochloric Acid SCHEMBL9843934 | 0.74 | CYP11B1 (0.53) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL24732609 | 0.74 | CYP11B1 (1.00) | CYP19A1CYP11B1CYP11B2TBXAS1FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0106060-B1 | IMIDAZOLE DERIVATIVES AND SALTS THEREOF, THEIR SYNTHESIS, AND PHARMACEUTICAL FORMULATIONS | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-09-28 | — | — | EP | disclosed |
| US-4562199-A | ANTICOAGULANTS | WELLCOME FOUNDATION LIMITED, A CORP OF ENGLAND (GB) | 1985-12-31 | — | — | US | disclosed |
| EP-0106060-A2 | Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-04-25 | — | — | EP | disclosed |