⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1064242 | 1.00 | — | — | |
| SCHEMBL7354674 | 0.95 | TSHR (0.31) | — | |
| SCHEMBL7354671 | 0.95 | TSHR (0.31) | — | |
| SCHEMBL2163214 | 0.83 | — | — | |
| SCHEMBL2163216 | 0.83 | — | — | |
| SCHEMBL2162625 | 0.81 | — | — | |
| SCHEMBL2162626 | 0.81 | — | — | |
| SCHEMBL2162600 | 0.79 | HMGCR (0.35) | — | |
| SCHEMBL8910819 | 0.79 | HMGCR (0.35) | — | |
| SCHEMBL2162598 | 0.79 | HMGCR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106795174-B | Antiviral active diazacyclospirodiketopiperazine alkaloid derivative and preparation method thereof | 扬州蓝色生物医药科技有限公司 | 2020-04-28 | — | — | CN | claimed |
| US-8486892-B2 | Blood coagulation factor inhibitors | NOVO NORDISK HEALTH CARE AG (CH) | 2013-07-16 | — | — | US | claimed |
| US-20110003752-A1 | New Blood Coagulation Factor Inhibitors | NOVO NORDISK HEALTH CARE A/G (CH) | 2011-01-06 | — | — | US | claimed |
| EP-2235042-A1 | NEW BLOOD COAGULATION FACTOR INHIBITORS | Novo Nordisk Health Care AG (CH) | 2010-10-06 | — | — | EP | claimed |
| WO-2009092758-A1 | NEW BLOOD COAGULATION FACTOR INHIBITORS | NOVO NORDISK HEALTH CARE AG (DK) | 2009-07-30 | — | — | WO | claimed |
| EP-4371979-A1 | FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT | Kumiai Chemical Industry Co., Ltd. (JP) | 2024-05-22 | — | — | EP | disclosed |
| CN-117693500-A | Carboxamide derivative and agricultural/horticultural plant disease control agent | 组合化学工业株式会社 | 2024-03-12 | — | — | CN | disclosed |
| WO-2024029475-A1 | WAVELENGTH CONVERSION FILM FORMING COMPOSITION | 日産化学株式会社 | 2024-02-08 | — | — | WO | disclosed |
| US-11753385-B2 | Method for producing kakeromycin and derivatives thereof | OP BIO FACTORY CO., LTD. (JP) | 2023-09-12 | — | — | US | disclosed |
| WO-2023286855-A1 | FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT | クミアイ化学工業株式会社 | 2023-01-19 | — | — | WO | disclosed |
| CN-115160248-A | Method for producing Kakeromycin and derivatives thereof | 海洋规划生物工厂株式会社 | 2022-10-11 | — | — | CN | disclosed |
| CN-114874131-A | Method for producing Kakeromycin and derivatives thereof | 海洋规划生物工厂株式会社 | 2022-08-09 | — | — | CN | disclosed |
| CN-1033227-C | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and their use. | SANKYO CO (JP) | 1996-11-06 | — | — | CN | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| CN-1072686-A | Has Pyrmidine nucleoside derivatives of anti-tumor activity and its production and use | SANKYO CO (JP) | 1993-06-02 | — | — | CN | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |
| US-4605645-A | ANTITUMOR AGENTS | TEIJIN LIMITED (JP) | 1986-08-12 | — | — | US | disclosed |
| EP-0081386-A1 | 5-Fluoro-2'-deoxyuridine derivatives and a process for the preparation thereof | TEIJIN LIMITED (JP) | 1983-06-15 | — | — | EP | disclosed |
| EP-0014984-B1 | GLUCOSAMINE-PEPTIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1982-12-01 | — | — | EP | disclosed |
| EP-0002677-B1 | GLUCOSAMINE-PEPTIDE DERIVATIVES AND THEIR PHARMACEUTICAL COMPOSITIONS | Takeda Chemical Industries, Ltd. (JP) | 1982-10-13 | — | — | EP | disclosed |