Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 18/20 | 0.64 |
| ▸ | RARB | P10826 | 16/20 | 0.64 |
| ▸ | RARA | P10276 | 16/20 | 0.64 |
| ▸ | RXRA | P19793 | 11/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | GMNN | O75496 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | THPO | P40225 | 1/20 | 0.64 |
| ▸ | MTOR | P42345 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10643296 | 1.00 | RARG (0.64) | RARGRARBRARARXRACYP3A4 | |
| SCHEMBL10644477 | 0.95 | RARG (0.64) | RARGRARBRARARXRACYP3A4 | |
| SCHEMBL10648535 | 0.95 | RARG (0.64) | RARGRARBRARARXRACYP3A4 | |
| SCHEMBL10644471 | 0.95 | RARG (0.64) | RARGRARBRARARXRACYP3A4 | |
| SCHEMBL10646273 | 0.90 | RARG (0.64) | RARGRARBRARARXRACYP3A4 | |
| SCHEMBL10646277 | 0.90 | RARG (0.64) | RARGRARBRARARXRACYP3A4 | |
| SCHEMBL10646080 | 0.90 | RARG (0.67) | RARGRARBRARARXRACYP3A4 | |
| SCHEMBL10646081 | 0.90 | RARG (0.67) | RARGRARBRARARXRACYP3A4 | |
| SCHEMBL10644097 | 0.89 | RARG (0.62) | RARGRARBRARARXRACYP3A4 | |
| SCHEMBL10644093 | 0.89 | RARG (0.62) | RARGRARBRARARXRACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232779-B1 | VINYL PHENOL DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF Aktiengesellschaft (DE) | 1988-10-12 | — | — | EP | disclosed |
| US-4714786-A | Vinylphenol derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1987-12-22 | — | — | US | disclosed |
| EP-0232779-A1 | Vinyl phenol derivatives, their preparation and their use | BASF Aktiengesellschaft (DE) | 1987-08-19 | — | — | EP | disclosed |