Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.61 |
| ▸ | THPO | P40225 | 2/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
| ▸ | CCKBR | P32239 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10924812 | 0.97 | MEN1 (0.61) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10352579 | 0.94 | MEN1 (0.61) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11356539 | 0.93 | MEN1 (0.58) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10374091 | 0.93 | MEN1 (0.57) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10925091 | 0.92 | CACNA1F (0.62) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11359144 | 0.91 | MEN1 (0.55) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10647518 | 0.90 | MEN1 (0.73) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11367829 | 0.90 | MEN1 (0.59) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10376258 | 0.89 | MEN1 (0.57) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10912924 | 0.89 | MEN1 (0.61) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0166296-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1,4-DIHYDROPYRIDINES | BAYER AG (DE) | 1988-10-12 | — | — | EP | disclosed |
| EP-0166296-A2 | Process for the preparation of optically active 1,4-dihydropyridines | BAYER AG (DE) | 1986-01-02 | — | — | EP | disclosed |
| EP-0026317-B1 | OPTICALLY ACTIVE 1,4-DIHYDROPYRIDINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | BAYER AG (DE) | 1985-10-16 | — | — | EP | disclosed |
| EP-0026317-A1 | Optically active 1,4-dihydropyridines, processes for their preparation and their use as medicaments | BAYER AG (DE) | 1981-04-08 | — | — | EP | disclosed |