Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10643866 | 1.00 | CTDSP1 (0.39) | CTDSP1ALDH1A1TDP1HSD17B10MAPT | |
| SCHEMBL10646275 | 0.90 | TDP1 (0.43) | CTDSP1ALDH1A1TDP1HSD17B10MAPT | |
| SCHEMBL10646266 | 0.90 | TDP1 (0.43) | CTDSP1ALDH1A1TDP1HSD17B10MAPT | |
| SCHEMBL10649189 | 0.90 | TDP1 (0.39) | CTDSP1ALDH1A1TDP1HSD17B10MAPT | |
| SCHEMBL10643816 | 0.90 | TDP1 (0.40) | ALDH1A1TDP1HSD17B10MAPTKMT2A | |
| SCHEMBL10643819 | 0.90 | TDP1 (0.40) | ALDH1A1TDP1HSD17B10MAPTKMT2A | |
| SCHEMBL10647955 | 0.89 | TDP1 (0.52) | ALDH1A1TDP1HSD17B10MAPTKMT2A | |
| SCHEMBL10871802 | 0.89 | TDP1 (0.52) | ALDH1A1TDP1HSD17B10MAPTKMT2A | |
| SCHEMBL10647950 | 0.89 | TDP1 (0.52) | ALDH1A1TDP1HSD17B10MAPTKMT2A | |
| SCHEMBL10643136 | 0.88 | KCNH2 (0.40) | CTDSP1ALDH1A1TDP1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057422-B1 | NEW CEPHEM COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-10-12 | — | — | EP | disclosed |