Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10277184 | 0.79 | PDE10A (0.50) | MAPTERN1RAB9ALMNAL3MBTL1 | |
| SCHEMBL10277537 | 0.78 | CCR1 (0.48) | MAPTERN1RAB9AALDH1A1LMNA | |
| SCHEMBL10644015 | 0.76 | KDM4E (0.49) | TLR8MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21555496 | 0.75 | TLR8 (0.60) | TLR8MAPTSLC2A1ALDH1A1TDP1 | |
| SCHEMBL1104421 | 0.75 | TLR8 (0.46) | TLR8MAPTSLC2A1RAB9AALDH1A1 | |
| SCHEMBL18799906 | 0.75 | TLR8 (0.46) | TLR8MAPTSLC2A1RAB9AALDH1A1 | |
| SCHEMBL10644280 | 0.74 | PDE10A (0.48) | MAPTCYP1A2CYP2C9CYP2C19SLC2A1 | |
| SCHEMBL23105463 | 0.72 | TLR8 (0.50) | TLR8MAPTSLC2A1ALDH1A1MEN1 | |
| SCHEMBL22894791 | 0.72 | PDE10A (0.36) | MAPTERN1RAB9AALDH1A1TDP1 | |
| SCHEMBL9611690 | 0.72 | TLR7 (0.61) | TLR8MAPTSLC2A1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4782050-A | BACTERICIDES | PFIZER INC. (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0276942-A1 | 6-Beta(substituted)-(S)-hydroxymethylpenicillanic acids and derivatives thereof | PFIZER INC. (US) | 1988-08-03 | — | — | EP | disclosed |