Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FNTA | P49354 | 7/20 | 0.39 |
| ▸ | FNTB | P49356 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.37 |
| ▸ | SQLE | Q14534 | 1/20 | 0.36 |
| ▸ | CBLB | Q13191 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10646201 | 1.00 | KMT2A (0.41) | KMT2AFNTAFNTBKDM4EATM | |
| SCHEMBL10571995 | 0.81 | KMT2A (0.39) | KMT2AFNTAFNTBKDM4EATM | |
| SCHEMBL10645188 | 0.81 | KMT2A (0.39) | KMT2AFNTAFNTBKDM4EATM | |
| SCHEMBL10645205 | 0.81 | KMT2A (0.39) | KMT2AFNTAFNTBKDM4EATM | |
| SCHEMBL10572002 | 0.81 | KMT2A (0.39) | KMT2AFNTAFNTBKDM4EATM | |
| SCHEMBL14135653 | 0.79 | FNTA (0.36) | KMT2AFNTAFNTBKDM4EATM | |
| SCHEMBL10577001 | 0.79 | KMT2A (0.38) | KMT2AFNTAFNTBKDM4EATM | |
| SCHEMBL10577002 | 0.79 | KMT2A (0.38) | KMT2AFNTAFNTBKDM4EATM | |
| SCHEMBL10577114 | 0.77 | PPARG (0.51) | KMT2AFNTAFNTBKDM4EATM | |
| SCHEMBL5369541 | 0.77 | PPARG (0.51) | KMT2AFNTAFNTBKDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0165439-B1 | POLYPRENYL COMPOUND, PROCESS OF PRODUCING IT AND PHARMACEUTICAL USE | Eisai Co., Ltd. (JP) | 1988-08-17 | — | — | EP | disclosed |