Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL693386 | 0.89 | HDAC6 (0.40) | CA14HDAC1HDAC2HDAC6EPHX2 | |
| SCHEMBL380584 | 0.88 | CA14 (0.45) | KDM4AKDM4CCA14METAP2HDAC1 | |
| SCHEMBL10646999 | 0.87 | CA14 (0.36) | KDM4AKDM4CCA14METAP2HDAC1 | |
| SCHEMBL9354393 | 0.86 | CA14 (0.44) | KDM4AKDM4CCA14METAP2HDAC1 | |
| SCHEMBL9354518 | 0.84 | CA14 (0.43) | KDM4AKDM4CCA14METAP2HDAC1 | |
| SCHEMBL7672284 | 0.84 | CA14 (0.43) | KDM4AKDM4CCA14METAP2HDAC1 | |
| SCHEMBL14735407 | 0.84 | CA14 (0.43) | KDM4AKDM4CCA14METAP2HDAC1 | |
| SCHEMBL1249634 | 0.84 | EPHX2 (0.43) | KDM4AKDM4CCA14HDAC1HDAC2 | |
| SCHEMBL23113130 | 0.83 | EPHX2 (0.45) | KDM4AKDM4CHDAC1HDAC2HDAC6 | |
| SCHEMBL8360181 | 0.83 | EPHX2 (0.45) | KDM4AKDM4CHDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215942-A4 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD. | SUMMERTON JAMES | 1988-08-23 | — | — | EP | disclosed |
| EP-0215942-A1 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD. | SUMMERTON JAMES | 1987-04-01 | — | — | EP | disclosed |
| WO-1986005519-A1 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD | SUMMERTON JAMES | 1986-09-25 | — | — | WO | disclosed |