Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10560991 | 0.81 | TSHR (0.54) | POLBAPOBEC3GLMNATSHRHTT | |
| SCHEMBL10517955 | 0.81 | HTT (0.56) | POLBAPOBEC3GLMNATSHRHTT | |
| SCHEMBL24022690 | 0.79 | KDM4E (0.40) | LMNATSHRHTTSMN1; SMN2MAPT | |
| SCHEMBL5647444 | 0.79 | NR1H2 (0.52) | POLBAPOBEC3GLMNATSHRHTT | |
| SCHEMBL1814417 | 0.78 | POLB (0.46) | POLBAPOBEC3GLMNATSHRHTT | |
| SCHEMBL10514565 | 0.75 | HTT (0.49) | POLBAPOBEC3GLMNATSHRHTT | |
| SCHEMBL24348447 | 0.75 | KDM4E (0.37) | LMNAMAPTALDH1A1 | |
| SCHEMBL10516389 | 0.73 | HPGD (0.62) | POLBAPOBEC3GLMNACA12CA1 | |
| SCHEMBL10522322 | 0.72 | MAPT (0.66) | LMNAHTTSMN1; SMN2MAPTKMT2A | |
| SCHEMBL179817 | 0.71 | NR1H2 (0.47) | LMNATSHRMAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273242-A2 | 2-Pyri(mi)dylthio-aryl ether | BAYER AG (DE) | 1988-07-06 | — | — | EP | disclosed |